Look at the bottom edge: Christus painted a tiny fly that seems to have landed on the frame, a trick to show off how real he could make things look. The monk's calm, weathered face is just as lifelike.
Shop / Portrait of a Carthusian

Portrait of a Carthusian
Petrus Christus · The Metropolitan Museum of Art
Petrus Christus, 1446. The Metropolitan Museum of Art, Open Access (public domain).